✦ LIBER ✦

Studies on isoxazole and pyrazole formation by the reaction of trifluoromethyl-substituted anilines with oxime and hydrazone dianions

✍ Scribed by Lucjan Strekowski; Shou-Yuan Lin

Publisher: Journal of Heterocyclic Chemistry
Year: 1997
Tongue: English
Weight: 211 KB
Volume: 34
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570340539

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

5‐(2‐Aminophenyl)isoxazoles are obtained in good yields by the reaction of 2‐(trifluoromethyl)aniline with dilithio derivatives of oximes of acetone, 3‐pentanone, propiophenone, and cyclohexanone. An analogous synthesis of a substituted isoxazole from 4‐(trifluoromethyl)aniline and 3‐pentanone oxime and the synthesis of a substituted pyrazole from 2‐(trifluoromethyl)aniline and 3‐pentanone hydrazone are less efficient.

📜 SIMILAR VOLUMES

ChemInform Abstract: Studies on Isoxazol

ChemInform Abstract: Studies on Isoxazole and Pyrazole Formation by the Reaction of Trifluoromethyl-Substituted Anilines with Oxime and Hydrazone Dianions.

✍ L. STREKOWSKI; S.-Y. LIN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 2 views

Studies on nucleophilic substitution rea

Studies on nucleophilic substitution reactions with cyclopentadienyliron complexes of some chloroarenes and nitroarenes and syntheses of substituted arenes by demetallation of the substitution products

✍ A.S. Abd-El-Aziz; C.C. Lee; A. Piórko; R.G. Sutherland 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 693 KB

Studies on the Reactions of Cyclic Oxaly

Studies on the Reactions of Cyclic Oxalyl Compounds with Hydrazines or Hydrazones: Synthesis and Reactions of 4-Benzoyl-1-(3-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic Acid.

✍ Ahmet Sener; Rahmi Kasimogullari; M. Kasim Sener; Ishak Bildirici; Yunus Akcamur 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 226 KB 👁 1 views

Studies on the reactions of cyclic oxaly

Studies on the reactions of cyclic oxalyl compounds with hydrazines or hydrazones : Synthesis and reactions of 4-benzoyl-1-(3-nitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid

✍ Ahmet Şener; M. Kasim Şener; Ishak Bildmci; Rahmi Kasimogullari; Yunus Akçamur 📂 Article 📅 2002 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 71 KB 👁 1 views

## Abstract The 1__H__‐pyrazole‐3‐carboxylic acid **2**, obtained from the furan‐2,3‐dione **1** and __N__‐Benzylidene‐__N__'‐(3‐nitrophenyl) hydrazine, was converted via reactions of its acid chloride **3** with various alcohols or N‐nucleo‐philes into the corresponding ester or amide derivatives