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Highly Stereoselective Trichloromethylation of N-(tert-Butylsulfinyl)aldimines: Facile Synthesis of Chiral α-Trichloromethylamines

✍ Scribed by Ya Li; Yunlv Cao; Jiaying Gu; Wei Wang; Han Wang; Tao Zheng; Zhihua Sun


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
369 KB
Volume
2011
Category
Article
ISSN
1434-193X

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## Abstract The first highly efficient and stereoselective difluoromethylation of structurally diverse __N‐tert__‐butylsulfinyl ketimines has been achieved with an in situ generated PhSO~2~CF~2~^−^ anion, which provides a powerful synthetic method for the preparation of a variety of structurally di