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Highly stereoselective axial addition of ethynyl carbanions to the carbonyl of cyclohexenones

โœ Scribed by Gilbert Stork; Jeffrey M. Stryker


Book ID
104250255
Publisher
Elsevier Science
Year
1983
Tongue
French
Weight
200 KB
Volume
24
Category
Article
ISSN
0040-4039

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On the highly stereoselective addition o
โœ Damian Dunford; Mathilde Guyader; Simon Jones; David W. Knight; Michael B. Hurst ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 147 KB

Addition of 2 equiv of a lithio-acetylide to an unprotected a-hydroxy ketone is extremely stereoselective in examples where the two ketone substituents are relatively large.