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Highly Stereocontrolled Formal Total Synthesis of Hemibrevetoxin B

โœ Scribed by Yoshinori Yamamoto; Isao Kadota


Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
952 KB
Volume
103
Category
Article
ISSN
0037-9646

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ChemInform Abstract: Stereocontrolled To
โœ I. KADOTA; Y. YAMAMOTO ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 28 KB ๐Ÿ‘ 2 views

Stereocontrolled Total Synthesis of Hemibrevetoxin B. -A linear approach to the total synthesis of title compound (I) is accomplished with high stereoselectivity in 56 steps and 0.75% overall yield from D-mannose. Key step in this synthesis is the intramolecular reaction of ฮณ-alkoxyallylstannanes wi