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Highly Sensitive LC Method with Automated Co-Sense System and Fluorescence Detection for Determination of Sertraline in Human Plasma

✍ Scribed by Nasr Y. Khalil; Ashraf M. Mahmoud; Ibrahim A. Darwish; Abdul-Rahman A. Al-Majed


Book ID
111791983
Publisher
Springer
Year
2010
Tongue
English
Weight
390 KB
Volume
71
Category
Article
ISSN
0009-5893

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## Abstract A sensitive, selective, simple and fast HPLC method based on the formation of derivative with fluorescamine was developed for the determination of memantine (ME) in human plasma. Separation was achieved on a CN column (200 mmΓ—4.6 mm) using acetonitrile–10 mM orthophosphoric acid contain