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A highly sensitive HPLC method with automated on-line sample pre-treatment and fluorescence detection for determination of reboxetine in human plasma

✍ Scribed by Nasr Y. Khalil


Book ID
116904002
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
493 KB
Volume
80
Category
Article
ISSN
0039-9140

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## Abstract A sensitive, selective, simple and fast HPLC method based on the formation of derivative with fluorescamine was developed for the determination of memantine (ME) in human plasma. Separation was achieved on a CN column (200 mmΓ—4.6 mm) using acetonitrile–10 mM orthophosphoric acid contain