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Highly selective synthesis of 1-polyfluoroaryl-1,2,3-triazoles via a one-pot three-component reaction

✍ Scribed by Cao, Liming; Liu, Cuibo; Tang, Xiangyang; Yin, Xuguang; Zhang, Bin


Book ID
125834603
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
578 KB
Volume
55
Category
Article
ISSN
0040-4039

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## Abstract The reactive 1 : 1 zwitterionic intermediate formed by the addition of isocyanides to dialkyl acetylenedicarboxylates was trapped with 4‐arylurazoles to produce the highly functionalized pyrazolo[1,2‐__a__][1,2,4]triazoles **5** in good yields (__Table__). The structures of the products