The diastereoselective reduction of acyclic B-alkoxy ketones with lithium aluminum hydride in the presence of lithium iodide has been studied and found to provide syn-1,3-diol derivatives with high diastereoselection. -The stereocontrolled formation of 1,3-diols is of great interest to synthetic che
✦ LIBER ✦
Highly Selective Reduction of Acyclic β-Alkoxy Ketones to Protected syn-1,3-Diols.
✍ Scribed by Aaron J. Cullen; Tarek Sammakia
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 27 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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