Maltitol was assigned unequivocally without any need for reference to model compounds by a combination of 2D, SIMPLE (secondary isotope multiplets of partially labelled entities) and DIS (differential isotope shift) NMR techniques. The combination of these three techniques is very powerful for the a
Highly Precise Measurement of Kinetic Isotope Effects Using 1 H-Detected 2D [ 13 C, 1 H]-HSQC NMR Spectroscopy
β Scribed by Manning, Kathryn A.; Sathyamoorthy, Bharathwaj; Eletsky, Alexander; Szyperski, Thomas; Murkin, Andrew S.
- Book ID
- 120248686
- Publisher
- American Chemical Society
- Year
- 2012
- Tongue
- English
- Weight
- 627 KB
- Volume
- 134
- Category
- Article
- ISSN
- 0002-7863
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The complete assignments of 1 H and 13 C signals of 19 pregnenolone and progesterone haptens were accomplished using twodimensional NMR techniques.
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## Abstract Twoβdimensional proton detected heteronuclear ^1^Hο£Ώ^13^C relayed coherence transfer, combined with 2D NOESY spectroscopy at 500 MHz, allowed the complete assignment of the ^13^C and ^1^H spectra of (__Z__)β17β[2β(triphenylstannyl)vinyl]β4βestrenβ17Ξ²βol. The conformation of this compound