✦ LIBER ✦
Structural and conformational characterization of (Z)-17-[2-(triphenylstannyl)vinyl]-4-estren-17β-ol using 2D proton detected 1H13C relay and 2D NOESY spectroscopy
✍ Scribed by François Kayser; Monique Biesemans; Huade Pan; Marcel Gielen; Rudolph Willem
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 497 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0749-1581
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✦ Synopsis
Abstract
Two‐dimensional proton detected heteronuclear ^1^H^13^C relayed coherence transfer, combined with 2D NOESY spectroscopy at 500 MHz, allowed the complete assignment of the ^13^C and ^1^H spectra of (Z)‐17‐[2‐(triphenylstannyl)vinyl]‐4‐estren‐17β‐ol. The conformation of this compound in solution was established from a 2D NOESY build‐up experiment and compared with the solid‐state structure obtained from previous x‐ray diffraction analysis. Proton–proton coupling constants were obtained from phase‐sensitive ^1^H double quantum filtered COSY spectroscopy.