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Highly Potent Triazole-Based Tubulin Polymerization Inhibitors

✍ Scribed by Zhang, Qiang; Peng, Youyi; Wang, Xin I.; Keenan, Susan M.; Arora, Sonia; Welsh, William J.


Book ID
121202514
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
198 KB
Volume
50
Category
Article
ISSN
0022-2623

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## Abstract Microtubules are the basic components of cell structure, which take part in a wide number of pivotal cellular functions. Drugs that are able to modulate the microtubule assembly either by inhibition of tubulin polymerization or by blocking microtubule disassembly are of great interest i