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Arylthioindoles, Potent Inhibitors of Tubulin Polymerization

✍ Scribed by De Martino, Gabriella; La Regina, Giuseppe; Coluccia, Antonio; Edler, Michael C.; Barbera, Maria Chiara; Brancale, Andrea; Wilcox, Elizabeth; Hamel, Ernest; Artico, Marino; Silvestri, Romano


Book ID
127344021
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
117 KB
Volume
47
Category
Article
ISSN
0022-2623

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## Abstract Microtubules are the basic components of cell structure, which take part in a wide number of pivotal cellular functions. Drugs that are able to modulate the microtubule assembly either by inhibition of tubulin polymerization or by blocking microtubule disassembly are of great interest i