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Highly Oxygenated Triterpenoids from the Marine Red Alga Laurencia mariannensis (Rhodomelaceae)

✍ Scribed by Nai-Yun Ji; Xiao-Ming Li; Hua Xie; Jian Ding; Ke Li; Lan-Ping Ding; Bin-Gui Wang

Publisher
John Wiley and Sons
Year
2008
Tongue
German
Weight
178 KB
Volume
91
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Two new and one known squalenoid‐derived triterpenoids, namely, laurenmariannol (1) and (21__α__)‐21‐hydroxythyrsiferol (2), and the known thyrsiferol (3) were isolated and identified from the marine red alga Laurencia mariannensis, which was collected off the coast of Hainan and Weizhou Islands of China. The structures of these compounds were established by means of spectroscopic analyses, as well as by comparison with literature data. Compounds 1 and 2 displayed significant cytotoxic activity against P‐388 tumor cells with IC~50~ values of 0.6 and 6.6 μg/ml, respectively.

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