We report a highly polymorphic, sequencetagged microsatellite site (STMS) at the D5S99 locus that was previously identified by a less informative restriction fragment length polymorphism (RFLP). This marker, which was also localized to the physical map of chromosome 5q by fluorescent in situ hybridi
β¦ LIBER β¦
Highly informative dinucleotide repeat polymorphism at the D11S29 locus on chromosome 11q23
β Scribed by L. Warnich; I. Groenewald; L. Theart; A. E. Retief
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 237 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0340-6717
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β¦ Synopsis
The informativeness of locus D11S29 as a genetic marker was improved by the identification of a highly polymorphic (GT)n repeat within the locus. Ten alleles were identified in parents of 40 Centre d'Etude du Polymorphisme Humain families and the polymorphism information content (PIC) was 0.77. The increased PIC value thus enables refinement of the linkage map of 11q23.
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