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Highly Functionalized Organomagnesium Reagents Prepared Through Halogen—Metal Exchange

✍ Scribed by Paul Knochel; Wolfgang Dohle; Nina Gommermann; Florian F. Kneisel; Felix Kopp; Tobias Korn; Ioannis Sapountzis; Viet Anh Vu


Publisher
John Wiley and Sons
Year
2003
Weight
54 KB
Volume
34
Category
Article
ISSN
0931-7597

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Preparation of Highly Functionalized Gri
✍ Laure Boymond; Mario Rottländer; Gérard Cahiez; Paul Knochel 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 107 KB 👁 2 views

At -40°C aryl iodides that contain other functional groups can be selectively converted into Grignard reagents, which react with electrophiles such as benzaldehyde in the usual manner [Eq. (a)]. Aryl bromides and iodides that are immobilized as esters on a Wang resin behave analogously.