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Highly Enantioselective Water-Compatible Organocatalyst for Michael Reaction of Ketones to Nitroolefins.

✍ Scribed by Vishnumaya Vishnumaya; Vinod K. Singh


Publisher
John Wiley and Sons
Year
2007
Weight
35 KB
Volume
38
Category
Article
ISSN
0931-7597

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## Abstract A highly diastereoselective and enantioselective Michael addition of cyclohexanone, acetone and other ketones to nitroolefins was developed by the use of an amine organocatalyst based on bispidine. Additionally, a theoretical study of transition structures revealed that this bispidine‐b