Highly enantioselective borane reduction of ketones catalyzed by chiral oxazaborolidines. Mechanism and synthetic implications
β Scribed by Corey, E. J.; Bakshi, Raman K.; Shibata, Saizo
- Book ID
- 115314845
- Publisher
- American Chemical Society
- Year
- 1987
- Tongue
- English
- Weight
- 380 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0002-7863
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Enantioselective Borane Reduction of Ketones Catalyzed by Chiral Lanthanum Alkoxides. -The enantioselective reduction of simple unfunctionalized ketones (I) is achieved by borane in the presence of a preformed catalyst from (R)-binaphthol and lanthanum triisopropoxide. -(ZHANG,
Highly Enantioselective Reduction of Prochiral Ketones with N,N-Diethylaniline β’ borane (DEANB) in Oxazaborolidine-Catalyzed Reductions. -A variety of prochiral ketones (I) is enantioselectively reduced to the corresponding alcohols (II) using diethylaniline borane in the presence of a chiral oxazab