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Highly Enantioselective Aza-Baylis–Hillman Reactions Catalyzed by Chiral Thiourea Derivatives

✍ Scribed by Izzat T. Raheem; Eric N. Jacobsen


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
165 KB
Volume
347
Category
Article
ISSN
1615-4150

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✍ Yong-Ling Shi; Min Shi 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 153 KB 👁 2 views

## Abstract A new kind of bifunctional (thio)urea‐phosphine catalyst was synthesized and applied to the aza‐Morita–Baylis–Hillman reaction of __N__‐sulfonated imines with methyl vinyl ketone, phenyl vinyl ketone, ethyl vinyl ketone or acrolein. Moderate to excellent __ee__ and yields of the product