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Highly Enantioselective and Regioselective Copper-Catalyzed 1,4 Addition of Grignard Reagents to Cyclic Enynones

✍ Scribed by Tissot, Matthieu; Pérez Hernández, Alexandra; Müller, Daniel; Mauduit, Marc; Alexakis, Alexandre


Book ID
126236258
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
513 KB
Volume
13
Category
Article
ISSN
1523-7060

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Enantioselective Copper-Catalyzed 1,4-Ad
✍ Maurus Spescha; Grety Rihs 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 German ⚖ 693 KB

The enantioselective copper-catalyzed 1,4-addition of Grignard reagents to a$-unsaturated carbonyl compounds was studied with the following Cu' compounds as catalyst precursor and 1,2 : 5,6-di-0 -isopropylidene-3thio-a -o-glucofuranose (Hsiig) as chiral ligand: CuI, iodo[bis(dibutylsulfide)]copper(I