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Highly Efficient Threonine-Derived Organocatalysts for Direct Asymmetric Aldol Reactions in Water

✍ Scribed by Xiaoyu Wu; Zhaoqin Jiang; Han-Ming Shen; Yixin Lu

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
74 KB
Volume
349
Category
Article
ISSN
1615-4150

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L-Prolinethioamides – Efficient Organoca
L-Prolinethioamides – Efficient Organocatalysts for the Direct Asymmetric Aldol Reaction
✍ Dorota Gryko; RadosΕ‚aw LipiΕ„ski πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 81 KB πŸ‘ 1 views

## Abstract A series of novel L‐proline derived thioamides has been synthesised. They have been evaluated as organocatalysts in the direct asymmetric aldol reaction for the first time. Thioamides exhibit catalytic ability higher than proline itself and the model aldol reaction of 4‐cyanobenzaldehyd