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Highly Efficient Synthesis of Steroidal Hydroxamic Acid Derivatives via Homogeneous Catalytic Carbonylation Reaction

✍ Scribed by Zsolt Szarka; Rita Skoda-Földes; László Kollár; Zoltán Berente; Judit Horváth; Zoltán Tuba


Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
99 KB
Volume
56
Category
Article
ISSN
0040-4020

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Facile Synthesis of Steroidal Phenyl Ket
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AbstractÐSteroidal phenyl ketones were synthesised in high yields by palladium-catalysed carbonylation reactions of 17-iodo-androst-16-ene derivatives in the presence of NaBPh 4 under mild reaction conditions. Alkenyl bromides or enol tri¯ates gave lower yields in the same reaction.