Highly efficient lipase-catalyzed asymmetric synthesis of chiral glycerol derivatives leading to practical synthesis of s-propranolol
β Scribed by Yoshiyasu Terao; Masakazu Murata; Kazuo Achiwa; Toshiyuki Nishio; Minoru Akamtsu; Minoru Kamimura
- Book ID
- 108381760
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 203 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
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The neutral (22,43)-MCCPM-rhodium complex was found to be an efficient catalyst for asymmetric hydrogenation of o-aminoacetophenone derivatives. A practical asymmetric synthesis of (S)-(-)-levamisole was realized by using this hydrogenation as a key reaction.
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