Highly Efficient Chemoselective Deprotection of O,O -Acetals and O,O -Ketals Catalyzed by Molecular Iodine in Acetone
β Scribed by Sun, Jianwei; Dong, Yanmei; Cao, Liya; Wang, Xinyan; Wang, Shaozhong; Hu, Yuefei
- Book ID
- 120210857
- Publisher
- American Chemical Society
- Year
- 2004
- Tongue
- English
- Weight
- 94 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0022-3263
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Efficiency and structural specificity earmark the reaction of phosphonium ions 1 with cyclic acetals and ketals to yield 1,3,2-dioxaphospholanium ions 2 [Eq. (1)]. Potential applications of this reaction are in monitoring trace levels of organophosphorus esters and in developing novel carbonyl depro
A novel and catalytic method is described for the selective deprotection of S,S-and S,O-acetals and ketals in the presence of their O,O-analogs to their corresponding carbonyl compounds based on the use of N-bromosuccinimide (NBS), N-chlorosuccinimide (NCS), 2,4,4,6-tetrabromo-2,5-cyclohexadiene-1-o