Highly efficient amphiphilic cleavage of γ-iodo carbonyl substrates with aluminum tris(2,6-diphenylphenoxide)t-BuLi system

✍ Scribed by Yuichiro Kondo; Kana Kon-i; Takashi Ooi; Keiji Maruoka

• Book ID: 104262496
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 220 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)01718-9

✦ Synopsis

A conceptually new amphiphilic cleavage of the ¢xl~ C-C bonds of y-iodo carbonyl substrates has been realized by the effective use of a combined Lewis acid/base system consisting of aluminum tris(2,6-diphenylphenoxide) (ATPH)/t-BuLi. This new amphiphilic bond cleavage reaction can be applied to a wide variety of ¥-iodo carbonyl substrates and therefore serves as a highly efficient and general route to both cyclic and acyclic unsaturated carbonyl compounds.