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Highly effective DNA in stimulating poly(ADP-ribose) polymerase reaction

โœ Scribed by Tomotaka Hashida; Hajime Ohgushi; Koichiro Yoshihara


Book ID
118313877
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
453 KB
Volume
88
Category
Article
ISSN
0006-291X

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Poly(ADP-ribose) polymerase in DNA damag
โœ Viatcheslav A. Soldatenkov; Mark Smulson ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 301 KB

Poly(ADP-ribose) polymerase (PARP) catalyzes the transfer of successive units of ADP-ribose moiety from NAD ุ‰ covalently to itself and other nuclear acceptor proteins. PARP is a zinc finger-containing protein, allowing the enzyme to bind to either double-or single-strand DNA breaks without any appar