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Highly Diastereoselective Oxy-Michael Additions of Enantiopure δ-Lactol Anions to Nitroalkenes: Asymmetric Synthesis of 1,2-Amino Alcohols

✍ Scribed by Nicola J. Adderley; David J. Buchanan; Darren J. Dixon; Dramane I. Lainé


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
112 KB
Volume
42
Category
Article
ISSN
0044-8249

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Diastereoselective 1,2-Addition of Organ
✍ Shin-ichi Fukuzawa; Daisuke Tsuchiya; Kae Sasamoto; Kohki Hirano; Makoto Ohtaguc 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 341 KB 👁 2 views

The chiral formylferrocenes 2-5 have been readily prepared in good yields by ortho-lithiation of the TMS-blocked orunblocked aminoferrocenes and subsequent reaction with DMF. The stereochemistry of the reaction of 2 with organometallic reagents has been examined. Reactions of 2 with Grignard and org