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Highly Chemoselective Oxidation of Dithioester Enethiolates to Sulfenates: Application to the Synthesis of Ketene Dithioacetal S-Oxides.

โœ Scribed by Franck Sandrinelli; Gaelle Fontaine; Stephane Perrio; Pierre Beslin


Publisher
John Wiley and Sons
Year
2005
Weight
32 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract Reaction of cyclopropanecarbaldehyde (I) with aryltitanium reagents, followed by tinโ€catalyzed retroโ€aldolโ€”acetalizationโ€”lactonization sequence provides access towards ฮณโ€aryllactones, e.g. (IV)/(V), with moderate to high diastereoselectivity.