Highly chemoselective oxidation of 1,5-diols to δ-lactones with TEMPO/BAIB

✍ Scribed by T.Matthew Hansen; Gordon J. Florence; Priscilla Lugo-Mas; Jiehao Chen; Jason N. Abrams; Craig J. Forsyth

• Book ID: 104252600
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 146 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)02489-9

✦ Synopsis

The selective oxidative conversion of a variety of highly functionalized 1°,2°-1,5-diols into the corresponding d-lactones has been effected simply and efficiently using a reagent system comprised of catalytic 2,2,6,6-tetramethylpiperidinooxy (TEMPO) and excess bis-acetoxyiodobenzene (BAIB).