No coin nor oath required. For personal study only.
Barshes et al. have provided a detailed and informative review of the role of liver transplantation in an infrequent condition, end-stage liver failure due to graft-versus-host disease (GVHD) after bone marrow transplantation. The authors reviewed cases collected from their own experience, English-speaking medical literature, and the United Network for Organ Sharing liver transplant registry. The one-and five-year patient survival rates were 72% and 63%, respectively. No deaths or liver failures were attributed to hepatic GVHD recurrence. Their review points out that some of the patients had cutaneous GVHD and others had intestinal GVHD. Those with cutaneous GVHD had an acceptable outcome. The authors concluded that concurrent cutaneous manifestation should not be a contraindication for liver transplantation; however, for concurrent intestinal GVHD more data are needed.
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Villamil et al. have provided a useful distinction when a transplant physician faces a low C2 value in the immediate port-transplant period, between poor absorption versus delayed but adequate CsA absorption. This distinction should prevent the risk of CsA toxicity when the underlying problem is del
## Immunosuppression and Donor Age With Respect to Severity of HCV Recurrence After Liver Transplantation Older donors have been reported to be associated with increased late mortality and increased fibrosis among patients transplanted for hepatitis C virus (HCV) cirrhosis. On the other hand, this