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Higher Expression of Topoisomerase II in Lung Cancers Than Normal Lung Tissues: Different Expression Pattern from Topoisomerase I

✍ Scribed by T. Hasegawa; K. Isobe; I. Nakashima; K. Shimokata

Book ID
115573435
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
401 KB
Volume
195
Category
Article
ISSN
0006-291X

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n sylvan la (K. B.T.) DNA was prepared from normal tissue and I9 lung cancer cell lines. Using probes which detect restriction fragment length polymorphisms at both the topoisomerase II u and p loci, heterozygosity was detected at a frequency of 0. I 7 and 0.37 for the