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Higher-End Serotonin Receptors: 5-HT5, 5-HT6, and 5-HT7

✍ Scribed by Richard A. Glennon


Publisher
John Wiley and Sons
Year
2003
Weight
50 KB
Volume
34
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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## Abstract We have studied the effects of 5‐HT~1A~ and 5‐HT~7~ serotonin receptor activation in hippocampal CA3‐CA1 synaptic transmission using patch clamp on mouse brain slices. Application of either 5‐HT or 8‐OH DPAT, a mixed 5‐HT~1A~/5‐HT~7~ receptor agonist, inhibited AMPA receptor‐mediated ex

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Dopamine (DA) release in the striatum is regulated by 5-hydroxytryptamine (5-HT, serotonin) through putative heteroreceptors. However, the effect of 5-HT is controversial. The present study investigated the effects of different 5-HT receptor ligands on DA release in the rat striatum by using in vivo