𝔖 Bobbio Scriptorium
✦   LIBER   ✦

High α-amylase activity in the syncytiotrophoblastic cells of first-trimester human placentas

✍ Scribed by Susan J. Fisher; Roger A. Laine

Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
569 KB
Volume
22
Category
Article
ISSN
0730-2312

No coin nor oath required. For personal study only.

✦ Synopsis

The syncytiotrophoblastic brush border of the human placenta forms the maternalfetal interface and is an important determinant of placental function. Electron micrographs of fresh brush border preparations isolated from first-trimester human placentas showed membrane vesicles, open-ended microvilli, and numerous glycogen particles. Analysis of the microvillar membranes for several plasma and intracellular membrane markers showed a high degree of purification, comparable to the results reported for the isolation of microvilli from full-term human placentas. The microvillar preparations from first-trimester placentas, however, also contained the enzymes necessary to synthesize and degrade glycogen. The degradation resulted in the accumulation of maltotriose and maltotetraose, apparently due to the action of a liver-type a-amylase. The occurrence of this enzyme and the enzymes for synthesizing glycogen in this brush border fraction is probably associated with the necessity for an extremely active glucose transport and liverlike storage system within the fetal tissue at this fetal-maternal membrane interface.

📜 SIMILAR VOLUMES

Degradation of extracellular matrix by t
Degradation of extracellular matrix by the trophoblastic cells of first-trimester human placentas
✍ Susan J. Fisher; Mark S. Leitch; Marsha S. Kantor; Carol B. Basbaum; Randall H. 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 917 KB

First-trimester human placental villi were cultured on 3H-leucine-labeled extracellular matrices isolated from the PF HR9 and PYS-2 cell lines. Both cell lines produced an extracellular matrix that contained basement membrane-specific macromolecules, including type IV collagen, laminin and proteogly

Monoclonal antibody to human T-cell leuk
Monoclonal antibody to human T-cell leukemia virus P19 defines polypeptide antigen in human choriocarcinoma cells and syncytiotrophoblasts of first-trimester placentas
✍ Dr. Jukka Suni; Ale Närvänen; Torsten Wahlström; Pentti Lehtovirta; Antti Vaheri 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 781 KB

## Abstract In previous studies we detected retrovirus RD114 p30‐related antigen in human placental syncytiotrophoblasts and antibodies in cord blood sera. We now report that a monoclonal IgG antibody specific for the p19 protein of human T‐cell leukemia virus (HTLV) reacts with human syncytiotroph

Ultrasonic assessment of the high rate o
Ultrasonic assessment of the high rate of human multiple pregnancy in the first trimester
✍ S. Levi 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 English ⚖ 355 KB

## Abstract The ultrasonic examination of 6, 690 pregnant patients showed a greater number of multiple pregnancies than usually observed at delivery: 71 per cent of twin gestations diagnosed before 10 weeks were singletons when delivered.

Absence of high levels of DNA polymerase
Absence of high levels of DNA polymerase α activity in the nuclear matrix prepared from mouse erythroleukemia cells
✍ Alberto M. Martelli; Luca M. Neri; Anna Maria Billi; Renato Bareggi; Lucio Cocco 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 453 KB

## Abstract We have examined the association of DNA polymerase α activity with the nuclear matrix prepared by different techniques from mouse erythroleukemia cells. At variance with the data obtained using other cell types we have found that only a small amount (less than 2%) of nuclear DNA polymer

Activation of human endothelial cells by
Activation of human endothelial cells by tumor necrosis factor-α results in profound changes in the expression of glycosylation-related genes
✍ Juan J. García-Vallejo; Willem Van Dijk; Bert Van Het Hof; Irma Van Die; Marten 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 271 KB

## Abstract The endothelium plays a central role in the logistics of the immune system by allowing the selective transmigration of leukocytes, as well as the maintenance of the circulation and coagulation homeostasis. Evidence is increasing that the carbohydrate composition of the endothelial cell