## Abstract Filicinic acid (5) was prepared in 75‐80% overall yield from 4,4‐dimethyl‐2‐cyclohexenone (1). The key intermediate, tetrachlorodienone 2, underwent facile substitution of both β‐chlorine substituents by methoxide affording the bis enol ether 3 which was converted into dichlorofilicinic
✦ LIBER ✦
High Yield Synthesis of Filicinic Acid Based on the Polychlorination of 4,4-Dimethyl-2-Cyclohexenone. Part I: One-pot Synthesis of 2,3,5,6-Tetrachloro-4,4-Dimethyl-2,5-Cyclohexadienone
✍ Scribed by Laurent De Buyck; Roland Verhé; Norbert De Kimpe; Niceas Schamp
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 290 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0037-9646
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