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High throughput screening for small molecule inhibitors of heparin-induced tau fibril formation

✍ Scribed by Alex Crowe; Carlo Ballatore; Edward Hyde; John Q. Trojanowski; Virginia M.-Y. Lee

Book ID
116294655
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
452 KB
Volume
358
Category
Article
ISSN
0006-291X

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## Abstract Amyloidβ€…Ξ² peptide (AΞ²) fibril formation is widely believed to be the causative event of Alzheimer’s disease pathogenesis. Therapeutic approaches are therefore in development that target various sites in the production and aggregation of AΞ². Herein we present a high‐throughput screening