Frontal affinity chromatography coupled online to mass spectrometry (FAC/MS) has previously been used to estimate binding constants for individual protein ligands present in mixtures of compounds. In this study FAC/MS is used to determine enzyme substrate kinetic parameters and binding constants for
β¦ LIBER β¦
High-Throughput Screening for Enzyme Inhibitors Using Frontal Affinity Chromatography with Liquid Chromatography and Mass Spectrometry
β Scribed by Ng, Ella S. M.; Yang, Feng; Kameyama, Akihiko; Palcic, Monica M.; Hindsgaul, Ole; Schriemer, David C.
- Book ID
- 126777119
- Publisher
- American Chemical Society
- Year
- 2005
- Tongue
- English
- Weight
- 506 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0003-2700
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