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High Throughput Screening Assay for UDP-Glucuronosyltransferase 1A1 Glucuronidation Profiling

✍ Scribed by Trubetskoy, O.V.; Finel, M.; Kurkela, M.; Fitzgerald, M.; Peters, N.R.; Hoffman, F.M.; Trubetskoy, V.S.

Book ID
120263914
Publisher
Mary Ann Liebert
Year
2007
Tongue
English
Weight
242 KB
Volume
5
Category
Article
ISSN
1540-658X

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## Abstract We have developed a new method based on specific primer extension reactions coupled with plate hybridization for high‐throughput genotyping of single‐base mutations. To improve the switching characteristics of the primer extension reaction, we introduced an artificial mismatch two bases