Screening of monoclonal antibody formula
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He, Feng (author);Woods, Christopher E. (author);Trilisky, Egor (author);Bower,
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Article
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2011
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John Wiley and Sons Inc.
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English
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The purpose of this study was to demonstrate the utility of combining a design of experiment (DOE) approach with high-throughput formulation screening to identify the main factors affecting protein thermostability and solution viscosity. The optimization of buffer compositions was guided by statisti