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High-throughput phagocytosis assay utilizing a pH-sensitive fluorescent dye

✍ Scribed by Beletskii, Anton; Cooper, Michael; Sriraman, Priya; Chiriac, Camelia; Zhao, Lihong; Abbot, Stewart; Yu, Liming


Book ID
119997689
Publisher
Informa plc
Year
2005
Tongue
English
Weight
306 KB
Volume
39
Category
Article
ISSN
0736-6205

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## Abstract Long‐chain fatty acid esters of 7‐(3,4‐dihydroxybutyloxy)‐2__H__‐1‐benzopyran‐2‐one (**6**) such as octanoate **2a** are shown to be exceptionally sensitive and selective fluorogenic substrates for lipases and esterases. Umbelliferone (**8**) is released upon hydrolysis of the ester fun