Directed evolution is becoming a widely used technique for modifying or enhancing protein performance. Ultimately, the success of directed protein evolution experiments hinges on the efficiency of the methods used to screen libraries for mutants with properties of interest. Although there is still a
High-Throughput Evaluation of the Wettability of Polymer Libraries
✍ Scribed by Jean-François Thaburet; Hitoshi Mizomoto; Mark Bradley
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 185 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1022-1336
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
A high‐throughput method for assessing the wettability of polymer libraries has been developed. Droplets of water are dispensed by a liquid handler onto polymer films, and a digital camera mounted on the robotic arm records the spread of the droplets. The surface area of the droplet (related to the contact angle) was measured by image processing software. This method is fully automated and allows rapid wettability measurements of polymer libraries to be obtained.
Automated system for spreading area measurement of water droplets on polymer films.
magnified imageAutomated system for spreading area measurement of water droplets on polymer films.
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