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High-throughput Characterization of Intrinsically Disordered Proteins from the Protein Structure Initiative

✍ Scribed by Johnson, Derrick E.; Sickmeier, Megan D.; Meng, Jingwei; Le Gall, Tanguy; Uversky, Vladimir; Dunker, A. Keith


Book ID
122275841
Publisher
Biophysical Society
Year
2009
Tongue
English
Weight
35 KB
Volume
96
Category
Article
ISSN
0006-3495

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The degradation of the majority of cellular proteins is mediated by the proteasomes. Ubiquitin -dependent proteasomal protein degradation is executed by a number of enzymes that interact to modify the substrates prior to their engagement with the 26S proteasomes. The 26S proteasome is made of two co