A High-Throughput Radiometric Assay for
โ
Mauro Cerretani; Laura Di Renzo; Sergio Serafini; Alessandra Vitelli; Nadia Genn
๐
Article
๐
1999
๐
Elsevier Science
๐
English
โ 127 KB
A novel radiometric in vitro assay for discovery of inhibitors of hepatitis C viral protease activity, suitable for high-throughput screening, was developed. The NS3 protein of hepatitis C virus (HCV) contains a serine protease, whose function is to process the majority of the nonstructural proteins