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High-Temperature Liquid Chromatography Coupled On-Line to a Continuous-Flow Biochemical Screening Assay with Electrospray Ionization Mass Spectrometric Detection

✍ Scribed by de Boer, Arjen R.; Alcaide-Hidalgo, Juan M.; Krabbe, Johannes G.; Kolkman, Jeffrey; van Emde Boas, Caspar N.; Niessen, Wilfried M. A.; Lingeman, Henk; Irth, Hubertus

Book ID
126136484
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
335 KB
Volume
77
Category
Article
ISSN
0003-2700

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## Abstract A method based on solid‐phase extraction coupled to liquid chromatography with positive ion electrospray ionization and tandem mass spectrometric detection was developed for the determination of didanosine in human serum, using lamivudine as internal standard. The acquisition was perfor