It is well recognised that high-risk human papillomaviruses (HPVs) are spread by sexual activity, but the possibility of non-sexual transmission remains controversial. We present evidence for vertical transmission from at least 30% HPV positive mothers to their infants, resulting in persistent infec
High risk genital papillomavirus infections are not spread vertically
✍ Scribed by Joakim Dillner; Agneta Andersson-Ellström; Björn Hagmar; John Schiller
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 171 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1052-9276
No coin nor oath required. For personal study only.
✦ Synopsis
The Medline-indexed literature on risk factors for HPV infection and HPV transmission is critically reviewed. Principles for assay validation and interpretation, reliability of different study designs and principles for interpretation of conflicting reports are discussed. The conclusions arrived at can be summarised as: (1) There is overwhelming epidemiological evidence that the only quantitatively important mode of transmission of infection with oncogenic genital HPV types is sexual. (2) There is also evidence that benign genital HPV types can be transmitted sexually, but the epidemiological data on the benign virus types are less extensive and less clear. (3) Perinatal HPV transmission is unequivocally demonstrated only for the rare disease juvenile respiratory papillomatosis.
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## Abstract Human papillomavirus (HPV) infection is associated with high‐grade vulvar intraepithelial neoplasia (VIN‐3). The prevalence of anogenital HPV infection in women with previously treated VIN‐3 has not been documented yet. This cross‐sectional study compared high‐risk HPV DNA detection rat