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High-resolution Mass Spectrometry and Accurate Mass Measurements with Emphasis on the Characterization of Peptides and Proteins by Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry

โœ Scribed by Russell, David H.; Edmondson, Ricky D.

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
434 KB
Volume
32
Category
Article
ISSN
1076-5174

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โœฆ Synopsis

Fundamental concepts of high-resolution mass spectrometry as it relates to the issue of accurate mass measurements are presented. Important issues speciรc to magnetic sector instruments, Fourier transform ion cyclotron resonance and time-of-ร‘ight (TOF) methods are discussed. Recent high-resolution TOF measurements on peptides and proteins, ionized by matrix-assisted laser desorption/ionization (MALDI), are presented and discussed in terms of basic concepts important to accurate mass measurements.

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