## Abstract Loss of chromosome arm 8p, sometimes in combination with amplification of proximal 8p, is found in urothelial carcinoma (UC) and other epithelial cancers and is associated with more advanced tumor stage. We carried out array comparative genomic hybridization on 174 UC and 33 UC cell lin
High-resolution genome-wide analysis of chromosomal alterations in elastofibroma
✍ Scribed by Juan Luis García Hernández; Javier Ortiz Rodríguez-Parets; José María Valero; María Asunción Gomez Muñoz; M. Rocío Benito; Jesus M. Hernandez; Agustín Bullón
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 403 KB
- Volume
- 456
- Category
- Article
- ISSN
- 1432-2307
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The identification of genetic aberrations may help understand the mechanisms of tumorigenesis and has important implications in diagnosis, prognosis and treatment. We applied Illumina's 317K high‐density single nucleotide polymorphism (SNP) arrays to profile chromosomal aberrations in c
## Abstract Neurofibromatosis Type I (NF1) is an autosomal dominant disorder characterized by the development of both benign and malignant tumors. The lifetime risk for developing a malignant peripheral nerve sheath tumor (MPNST) in NF1 patients is ∼10% with poor survival rates. To date, the molecu
## Abstract We used array‐based comparative genomic hybridization (aCGH) to measure genomic copy number alterations (CNAs) in 42 neuroblastoma cell lines with known 1p36.3, 2p24 (__MYCN__), 11q23, and 17q23 allelic status. All cell lines showed CNAs, with an average of 22.0% of the genome of each s