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High resolution distribution of mRNA within the cytoskeleton

✍ Scribed by Gary J. Bassell

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
681 KB
Volume
52
Category
Article
ISSN
0730-2312

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✦ Synopsis

It has been well documented that mRNA is associated with the cytoskeleton, and that this relationship is involved in translation and mRNA sorting. The molecular components involved in the attachment of mRNA to the cytoskeleton are only poorly understood. The objective of this research was to directly visualize the interaction of mRNA with the cytoskeleton, with sufficient resolution to identify the filament systems involved. This work required the development of novel in situ hybridization methods for use with electron microscopy.

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