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High reliability and sensitivity of the BCR/ABL1 D-FISH test for the detection of BCR/ABL rearrangements

✍ Scribed by A. Pelz; H. Kröning; A. Franke; P. Wieacker; M. Stumm


Book ID
105988013
Publisher
Springer
Year
2002
Tongue
English
Weight
80 KB
Volume
81
Category
Article
ISSN
0939-5555

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Detection of BCR/ABL gene rearrangement
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Cytogenetic and molecular studies were performed on 20 interferon-␣ receiving Turkish chronic myelocytic leukemia patients. Four different restriction endonucleases and bcr-G probe were used for southern blot analysis to detect rearrangements of the bcr gene. The RT-PCR method was also applied to de