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High-Performance Thin-Layer Chromatography Method for Assessment of the Quality of Combinatorial Libraries, and Comparison with Liquid Chromatography−Ultraviolet−Mass Spectrometry

✍ Scribed by Salo, Piia K.; Pertovaara, Anniina M.; Salo, Vesa-Markku A.; Salomies, Hannele E. M.; Kostiainen, Risto K.


Book ID
126248918
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
122 KB
Volume
5
Category
Article
ISSN
1520-4766

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Liquid chromatography/electrospray mass spectrometry with selected-ion monitoring makes possible the visualization and positive identification of a family of isobaric ions from libraries comprising hundreds of peptides. For larger libraries (up to 10 5 peptides), a given peptide, known to be unique