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High-performance Thin-layer Chromatography for the Determination of Nimesulide in Human Plasma, and its Use in Pharmacokinetic Studies

โœ Scribed by K. K. PANDYA; M. C. SATIA; I. A. MODI; R. I. MODI; B. K. CHAKRAVARTHY; T. P. GANDHI


Book ID
118110550
Publisher
Pharmaceutical Press
Year
1997
Tongue
English
Weight
300 KB
Volume
49
Category
Article
ISSN
2042-7158

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Two specific methods for the simultaneous determination of nimesulide, a non steroidal anti-inflammatory drug, and its hydroxylated metabolite in human plasma are described. Adopting a high performance liquid chromatographic (HPLC) system with UV detection (230 nm), the compounds, extracted from pla