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High-performance liquid chromatographic separation of an HIV-1 reverse transcriptase inhibitor and its enantiomer

โœ Scribed by Tao Wang; Nelu Grinberg; Gary Bicker; Patricia Tway; Karen Thompson


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
355 KB
Volume
738
Category
Article
ISSN
1873-3778

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We report the development of a simple, economical and reliable chromatographic method for the simultaneous determination of six HIV protease inhibitors (PIs; amprenavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir), the active metabolite of nelfinavir (M8) and the non-nucleoside rever